|Type of medicine||Tricyclic antidepressant|
|Used for||Treatment of depression
Treatment of night-time bed-wetting in children
|Also called||Imipramine hydrochloride|
Imipramine works by preventing chemicals called serotonin and noradrenaline from being reabsorbed back into the nerve cells in the brain. This helps prolong the mood lightening effect of these chemicals, and so helps relieve depression.
Imipramine helps relieve bed-wetting by blocking certain receptors in the wall of the bladder and preventing a chemical called acetylcholine from acting on these receptors. Acetylcholine normally causes the bladder to empty, so by stopping this action, imipramine reduces the need to pass urine.